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LSZ, also known as lysergic acid 2,4-dimethylazetidide or LA-Azetidide, is a psychedelic lysergamide analog related to LSD. LSZ modifies the LSD molecule by incorporating a rigid 2,4-dimethylazetidine ring in place of the diethylamide group, leading to three possible diastereomers. The (S,S)-isomer (LA-SS-Az) is the most potent and widely used form, exhibiting psychedelic effects similar to LSD with a typical dose around 150 micrograms per blotter. It acts primarily as a non-selective serotonin receptor agonist, notably at 5-HT2A receptors, producing classic psychedelic effects. LSZ was developed for research on serotonin receptor interactions and psychopharmacology.
| Property | Details |
|---|---|
| Chemical Name | Lysergic acid 2,4-dimethylazetidide (LSZ) |
| CAS No | 470666-31-0 |
| Molecular Formula | C21H25N3O |
| Typical Dosage | 150 micrograms per blotter |
| Form | Blotter paper impregnated with LSZ powder |
| Purity | Typically ≥99%, verified by chromatography |
| Activity | Agonist at serotonin 5-HT2A, 5-HT1A, 5-HT2C receptors |
| Duration | Approximately 3 to 11 hours |
| Notes | Potent psychedelic with affinity similar to LSD |
Investigating serotonin receptor-mediated psychedelic effects
Studying ligand-receptor binding and signaling in 5-HT receptor pharmacology
Behavioral and neurochemical assessments in preclinical models
Analytical chemistry and forensic research on lysergamide analogs
Structure-activity relationship studies of LSD derivatives
Handle LSZ blotters with care using gloves and eye protection in a controlled lab environment. Avoid inhalation, ingestion, or skin contact outside of research protocols. Dispose of waste according to institutional guidelines. Not intended for human or veterinary use.
LSZ blotters are supplied in secure, tamper-evident packaging ensuring dosage and purity stability. Orders are available only to qualified research institutions, with shipping compliant with applicable regulations.
Store blotters in a sealed, light-resistant package at cool, dry conditions (~4 °C preferred) to maintain potency and stability.
Q: How potent is LSZ compared to LSD?
A: LSZ (S,S)-isomer is approximately equipotent or slightly more potent than LSD on a microgram basis.
Q: What receptors does LSZ target?
A: Non-selective serotonin receptor agonist with high affinity for 5-HT2A.
Q: What effects does LSZ produce?
A: Classic psychedelic effects similar to LSD including perceptual changes and altered cognition.
Q: How are blotters stored for longevity?
A: In cool, dry, light-protected environments, preferably refrigerated.
Order premium LSZ 150mcg blotters for advanced serotonergic psychedelic research. Verified purity and reliable dosing for your laboratory studies.
