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Lemmon 714 is a sedative and hypnotic medication. It was sold under the brand names Quaalude and Sopor among others, and sold as a combination drug under the brand name Mandrax which contained 300 mg methaqualone and 25mg diphenhydramine within the same tablet. Commercial production of methaqualone was halted due to widespread abuse and addictiveness. It is a member of the quinazolinone class.
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Beyond this, Lemmon also manufactured smaller quantities of the drug under a different name (Mequin). This allows doctors to prescribe methaqualone without the negative connotations brought about by ludes.
The rights to Quaalude were discontinued in the US in 1985.
Ultimately, it was a combination of the drug’s strong psychological addictiveness and widespread recreational abuse that led to the downfall of ludes.
By 1985, the drug was moved to Schedule I on the DEA’s list. Schedule I drugs are considered to have no legitimate medical use, a high potential for widespread abuse, and to be lacking in safety even when used under medical supervision.
According to DEA estimates, there were 20 million Quaaludes on the streets of the US in 1980, a number they projected would double within a year.
What happened, though, was the precise opposite, with the problem not only subsiding but being effectively eliminated in a matter of a few short years.
How did the DEA manage to win this war on drugs where all others seem to have roundly failed?
Well, with Quaaludes, this was accomplished by going after the source rather than the end-user. By targeting the manufacturers of methaqualone powder all over the work and inducing them to stop production, the US government worked tirelessly to put a stop to what was becoming a clear and present danger.
At the same time as this aggressive action, doctors started to use alternative treatments for insomnia, in large part due to the enormous stigma generated by Quaaludes.
President Reagan banned the domestic production and sales of Quaaludes in 1984.
Despite this, there are still labs making Quaaludes in Mexico and elsewhere in the world. The drug is also still found in India and South Africa, although under different names.
Quaalude Abuse and Quaalude Dependence
Abusing Quaaludes creates a dependence much as you would experience from barbiturates.
Tolerance quickly builds and more of the drug is needed to get the euphoric effects. This leads to an increased risk of overdose.
Abruptly discontinuing use leads to withdrawal symptoms that include:
- Irritability
- Restlessness
- Nausea
- Vomiting
- Nausea
- Weakness
- Insomnia
- Tremors
- Headache
- Mental confusion
- Seizures
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Quaalude: Understanding Its Effects, Risks, and Historical Context
What Are Quaaludes?
Definition and Classification
- Quaaludes, also known as methaqualone, are a central nervous system depressant.
- They were originally synthesized in the 1950s as a sedative-hypnotic drug.
- Quaaludes are classified as a Schedule II controlled substance due to their high potential for abuse and dependence.
History of Quaaludes
- Quaaludes were first introduced as a safer alternative to barbiturates in the 1960s.
- They gained popularity as a recreational drug in the 1970s, particularly among college students and in the disco and party scenes.
- The widespread recreational Quaalude abuse led to their ban in the United States in 1983.
Quaaludes Effects on the Central Nervous System
Physical Effects
- Quaaludes can cause drowsiness, dizziness, and impaired motor function.
- They can also lead to respiratory depression, coma, and death, especially when taken with alcohol.
- Physical dependence on Quaaludes can occur with prolonged use, leading to withdrawal when use is discontinued.
Psychological Effects
- Quaaludes can produce feelings of relaxation and euphoria, which can lead to psychological dependence.
- They can also cause anxiety, insomnia, and tremors when use is abruptly discontinued.
- Quaalude abuse can negatively impact mental health, leading to depression, anxiety, and mood swings.
Quaaludes Addiction and Physical Dependence
Signs and Symptoms of Addiction
- Taking Quaaludes in larger amounts or for longer periods than intended.
- Spending a lot of time obtaining or using Quaaludes.
- Continuing to use Quaaludes despite physical or mental health problems.
- Experiencing withdrawal symptoms when use is discontinued.
Risks of Physical Dependence
- Quaaludes can cause physical dependence, leading to withdrawal symptoms when use is discontinued.
- Withdrawal symptoms can include anxiety, insomnia, and tremors.
- Physical dependence on Quaaludes can increase the risk of overdose and toxicity.
Quaaludes Abuse and Risks
Overdose and Toxicity
- Quaaludes can cause coma, seizures, and death, especially when taken with alcohol.
- Methaqualone overdose can occur with oral administration of large doses.
- Widespread recreational Quaalude abuse has led to numerous reports of overdose and toxicity.
Interactions and Contraindications
- Quaaludes can interact with other central nervous system depressants, such as alcohol and benzodiazepines.
- They can also interact with certain medications, such as antidepressants and antihistamines.
- Quaaludes are contraindicated in patients with a history of substance abuse or dependence.
Treatment and Recovery from Quaaludes Addiction
Detoxification
- Detoxification from Quaaludes typically involves a medically supervised tapering of the drug.
- Detoxification can help manage withdrawal symptoms and reduce the risk of overdose and toxicity.
Therapeutic Interventions
- Mental health treatment, such as cognitive-behavioral therapy (CBT), can help address underlying issues contributing to Quaalude addiction.
- Group therapy and support groups can provide a sense of community and accountability during recovery.
Rehabilitation Programs
- Inpatient and outpatient rehabilitation programs can provide a structured environment for recovery.
- Rehabilitation programs can include medication-assisted treatment and mental health treatment like individual counseling and group therapy.
Quaaludes in the United States
Brand Names and Street Names
- Quaaludes were marketed under the brand name Quaalude in the United States.
- They were also known by street names, such as “ludes” and “sopers.”
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